4 Top Next Generation Sequencing Forums

Forums offer a great opportunity to mind share with like minded professionals across the globe. They offer a vehicle to ask and potentially receive quick answers to just about any industry related question. Forums also offer a vehicle for collaboration and improved decision making by harnessing the power of the crowd. So which are the top next gen sequencing forums? These 4 were selected for having the largest number of active members discussing next gen sequencing specifically.

Top Next Generation Sequencing Forums

  1. Seqanswers: A top list of NGS forums would not be complete without SEQanswers. This forum is dedicated solely to this topic. Seqanswers was founded to be an information resource and user-driven community focused on all aspects of next-generation genomics.
  2. Nature Network: Nature Network is a professional networking website for scientists around the world. It is not dedicated specifically to next generation sequencing but they do have many members active on the subject. Nature is an online meeting place where you and your colleagues can gather, share and discuss ideas, and keep in touch. It’s also where you can consult the community for answers to scientific questions or offer your expertise to help others.
  3. The Science Advisory Board: This forum has as its mission to improve communications between medical and life science professionals and the companies who provide this community with products and services. To accomplish this mission, The Science Advisory Board conducts studies about the products and services NGS professionals currently use. Companies value this information and use it to improve existing products and services or to develop new ones that better meet the needs of their customers.
  4. LinkedIn: Little explanation required. Here are the top 3 forums (based on the number of members)

Forums can be an extremely valuable tool in a career involving next generation sequencing (or otherwise), enabling both researchers and NGS providers a fantastic way to collaborate and build relationships. Undoubtedly there are other great next gen sequencing forums out there. If you have any you would like to share we would love to here about it!

Wyzer Biosciences Lists Services On the Genohub Next Generation Sequencing Market

Genohub would like to welcome Wyzer Biosciences to Genohub. The sequencing services listed by Wyzer will add more available options to the Genohub next generation sequencing market.

Wyzer listed next generation sequencing services for an Ion PGM 314 Chip.

Privately held, Wyzer Biosciences, Inc. was founded in 2011 and is located in dynamic Cambridge, MA, the home of Harvard, MIT and many other world-class educational and biotech institutions. Through their expertise in molecular biology they provide services to partners and collaborators in industry and academia that will aid them in their ongoing research. We look forward to matching Wyzer with the most compatible high throughput sequencing projects for their lab.

2 Ted Talks on the Next Generation Sequencing Impact

Here are a couple of great Ted Talks on the impact of next generation sequencing on a variety of areas that promise to fundamentally change our daily lives.

This is a good talk about the future of sequencing and the impact of massively parallel sequencing. The impact to patient care, food supply, health insurance, politics, and more are discussed.

Richard Resnick: Welcome to the genomic revolution:

http://embed.ted.com/talks/richard_resnick_welcome_to_the_genomic_revolution.html

 

More of an introductory discussion on gene sequencing. What is genomics? How will it affect our lives? In this intriguing primer on the genomics revolution, entrepreneur Barry Schuler says we can at least expect healthier, tastier food. He suggests we start with the pinot noir grape, to build better wines.

Barry Schuler: Genomics 101:

http://embed.ted.com/talks/barry_schuler_genomics_101.html

 

11 Top Next Generation Sequencing Blogs

Here is a compilation of some of the best next generation sequencing blogs for your reading pleasure:

CoreGenomics:

CoreGenomics is a personal blog written by James Hadfield who runs a genomics core facility in Cambridge. The core runs lots of next-generation sequencing and gene expression microarrays alongside other Genomic technologies.

Pathogens Genes and Genomes:

A heady mix of bacterial pathogenomics, next-generation sequencing, type-III secretion, bioinformatics and evolution.

Next-Gen Sequencing:

A working guide to the rapidly developing world of Next-Generation DNA sequencing, with an emphasis on bioinformatics.

BitesizeBio:

An eclectic blog of what could more adeptly be described as complete articles which are produced by a variety of authors with varying areas of focus.

Omics! Omics!:

A computational biologist, Dr Keith Robison’s personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery.

Genomes Unzipped:

Genomes Unzipped is a group blog providing expert, independent commentary on the personal genomics industry.

In Between Lines of Code:

A blog on Biology, sequencing, bioinformatics and more, by Lex Nederbragt who works at the University of Oslo at the Centre for Ecological and Evolutionary Synthesis (CEES).

Kevin’s GATTACA World:

Kevin Gattaca’s blog with a focus on bioinformatics, genome science and next generation sequencing.

Next Generation Technologist:

A blog by Dale Yuzuki, who is a marketing professional who currently works for Life Technologies Corporation and offers a unique perspective on next generation sequencing.

Blog @ Illumina:

Of course no next gen sequencing blog list would be complete without including the most prolific next gen sequencing instrument company in the world.

RNA-SeqBlog:

A blog focused on transcriptome sequencing news.

We hope you enjoy some of the blogs on this list. Please comment if I missed any other terrific next gen sequencing blogs.

 

Next Generation Sequencing Creates Opportunities for Software Entrepeneurs

Earlier this year it was announced that a large biotechnology firm, Qiagen based in the Netherlands completed its purchase of Ingenuity Systems based in California which had built software exclusively. This event is one of many to signal the trend of a merging of the biotechnology and software industries which is presenting a large opportunity for software entrepreneurs.

This trend, as further discussed on the Washington Post, is being led by the next generation sequencing industry which continues to produce sequencing data at ever increasing rates and at lower costs. As sequencing data becomes more readily available, the demand continues to rise as some experts suggest DNA mapping will become standard medical practice. Previously it had been difficult for software companies to thrive in the biotech space as next generation sequencing hadn’t come along until massively parallel signature sequencing (MPSS) was developed in the 1990’s. Because previous methods were costly and not readily available, the demand for sequencing analysis was held equally low.

As vast amounts of next generation sequencing data are now produced at ever quicker rates, there arises a tremendous opportunity for software entrepreneurs who are able to produce usable results from this data. Although the industry is in its infancy, and has not yet produced a clear market winner, there are several new companies which are capitalizing on this demand. One of these is Enlis Genomics which was started two years ago in Berkeley, CA by Devon Jensen, a PhD in molecular and cell biology. Devon saw the demand for software which was easy enough to use by the average researcher. Another notable example would be Cypher Genomics out of San Diego, CA also formed two years ago which allows researchers to detect genetic variations which may signal health concerns.

Undoubtedly we will also continue to see biotech firms of all types continue to gobble up these new bioinformatics companies as they strive to offer a complete front to back solution for their clients. This is truly an exciting time in the bioinformatics industry with a host of opportunities yet to be discovered.

The Institute for Personalized and Predictive Medicine of Cancer (IMPPC) Lists High Throughput Sequencing Services On the Genohub Market

We want to welcome The Institute for Personalized and Predictive Medicine of Cancer (IMPPC) to the Genohub family. The high throughput sequencing services listed by IMPPC will add more available options to the Genohub next generation sequencing market.

IMPCC listed the following next generation sequencing instruments and library prep options:

  • Instruments:
    • Illumina HiScanSQ
    • Ion PGM 314 Chip
    • Ion PGM 316 Chip
    • Ion PGM 318 Chip
  • Library prep:
    • Illumina Directional RNA (polyA-selected)
    • Illumina Small RNA (microRNA)
    • Ion DNA

The IMPCC is a publicly funded institute backed by a private foundation with a mission to advance in the understanding of genetic and epigenetic factors leading to higher predisposition or susceptibility to develop cancer. We look forward to matching IMPPC with the most compatible high throughput sequencing projects for their lab.

Next Generation Sequencing Promises to Increase IVF Success Rates

Next generation sequencing techniques hold promise for increasing the success rate of in-vitro fertilization (IVF). Dr Dagan Wells of the NIHR Biomedical Research Center at the University of Oxford announced on July 8, 2013 at the ESHRE annual meeting that an IVF birth had resulted, for the first time, due to embryo selection based on next generation sequencing results.

Historically, IVF success rates have stood at around 30%, thought to largely be due to DNA mutations in the embryo. Traditional sequencing techniques have been utilized in order to identify and utilize healthier embryos resulting in a higher success rate. The drawbacks, however, have been that these methods have been far too costly to be within reach of most patients.

Dr Wells and an international research team developed an embryo selection process using much faster and less costly next generation sequencing techniques. This process only takes about 16 hours avoiding the need for embryo freezing. Dr Wells technique also offers additional advantages when compared to previous techniques. Complete chromosome information can be produced and serious gene defects can be detected simultaneously.

As next generation sequencing has been revolutionizing many areas of genetic research, it looks poised to soon benefit IVF patients. “In the past few years, results from randomized clinical trials have suggested that most IVF patients would benefit from embryo chromosome screening, with some studies reporting a 50% boost in pregnancy rates. However, the costs of these genetic tests are relatively high, putting them beyond the reach of many patients. Next generation sequencing is a way which could make chromosome testing more widely available to a greater number of patients, improving access by cutting the costs. Our next step is a randomized clinical trial to reveal the true efficacy of this approach – and this will begin later this year.”  -Dr Wells

Genohub Next Generation Sequencing Market Open to Researchers

RESEARCHERS! SAVE TIME & MONEY ON YOUR NEXT NEXT GENERATION SEQUENCING PROJECT!

The Genohub next generation sequencing market opens today to a number of researchers who could benefit from placing their next-gen sequencing order through Genohub. If you would like to take part in our initial launch please visit our shopping page, enter a few bits of information such as the number of samples to sequence and minimum number of reads, or coverage per sample, and we will instantly match you with the best providers for your project. You also have the ability to search by specific technology if you require a service provider with specific platforms and library types. It is 100% free to search and place an order, and we are currently offering free consultation from our science staff.

Here are some of the other ways we help researchers on Genohub:

  1. Save time shopping for the best price on costly sequencing projects

  2. Eliminate the need for researching the technologies in order to find suitable sequencing solutions

  3. Offer more predictability on turnaround time and quality

  4. Centralized per-project communication platform

Of course we realize that you have a number of options available when it comes to finding the best next generation sequencing provider for your project. In fact, we developed Genohub to help researchers in ways that have not been available up until now. Genohub is unique in that we offer:

  1. Structured service listings

  2. Intelligent technology-aware software that automatically matches project requirements with providers’ service listings

  3. Shopping, ordering and project management process tailored to sequencing projects

As a researcher, we encourage you to visit our shopping page and let us know what you think! And of course if you need any assistance along the way, we would be more than glad to help.