The yearly genomics pilgrimage to Marco Island begins next Wednesday from Feb. 12th until the 15th. The 15th Advances in Genome Biology and Technology (AGBT 2014) Agenda was released last week, it’s guaranteed not to disappoint. We expect the following lectures to be the most interesting: 

Aviv Regev, Broad Institute of MIT and Harvard
“Harnessing Variation Between Single Cells to Decipher Intra and Intercellular Circuits in Immune Cells”

-Single cell genomics is becoming an extremely useful tool, we’re eager to hear more on the first day of the meeting. 

Jeanne Lawrence, University of Massachusetts Medical School
“Silencing Trisomy 21 for Genome Balance in Down Syndrome Stem Cells”

– Her talk was the most tweeted plenary lecture during ASHG 2013 and it was great! A must go!

Evan Eichler, University of Washington
“Advances in Sequencing Technology Identify New Mutations, Genes and Pathways Related to Autism”

– Dr. Eichler studies gene duplication and DNA transposition within the human genome. This is going to be a good talk.

Beth Shapiro, University of California, Santa Cruz
“Paleogenomes, Ice-age Megafauna, and Rapid Warming: How Genomes From the Past Can Help Predict the Consequences of the Future Climate Change”

 – The paleogenomics section of the recent PAG conference was excellent. I expect this to be an interesting lecture as well. 

 Andrea Kohn, University of Florida
“Single-Neuron Semiconductor RNA-seq with Nanofluidic Capture: Toward Genomic Dissection of the Complex Brains and Memory Circuits”

– Lots of good RNA-Seq talks. Dr. Kohn’s single cell sequencing approach is described here: Single-neuron transcriptome and methylome sequencing for epigenomic analysis of aging  and here: Single-cell semiconductor sequencing.

Stephen Fodor, Cellular Research, Inc.
“Digital Encoding of Cellular mRNAs Enables Precise and Absolute Gene Expression Analysis by Single-Molecule Counting”

– What’s next from the founder of Affymetrix? For a preview check out their paper that came out this month on molecular indexing for quantitative targeted RNA-Seq.

 James Hadfield, Cancer Research, UK
“Monitoring Cancer Genome Evolution with Circulating Tumour DNA Exome Sequencing”

– Looks interesting. Hoping to get a preview from his blog: CoreGenomics. 

Hiroyuki Aburatani, The University of Tokyo
“Single Cell RNA Sequencing Reveals Transition of Cell Populations with Epigenomic Switch in Cell Fate Determination Along Cardiomyocyte Differentiation”

Brian Haas, Broad Institute of MIT and Harvard
“Single Cell Developmental Genomics: Trinity-Enabled Single Cell Transcriptome Study Identifies New Regulators of Salamander Limb Regeneration”

 David Jaffe, Broad Institute of MIT and Harvard
“Assembly of Bacterial Genomes Using Long Nanopore Reads”

– Expecting to see some of the first Nanopore data here !

W.R. McCombie, Cold Spring Harbor Laboratory
“A Near Perfect de novo Assembly of a Eukaryotic Genome Using Sequence Reads of Greater than 10 Kilobases Generated by the Pacific Biosciences RS II”

Hesaam Esfandyarpour, Genapsys, Inc.
“The GENIUS™ Platform: A Next Generation Sequencing Platform That Exceeds Quality and Cost Goals for Universal Deployment In and Out of Core Laboratory Environments”

– The latest NGS platform, Genapsys just got $37M in series B financing. 

 Zak Wescoe, University of California, Santa Cruz
“Error Rates for Nanopore Discrimination Among Cytosine and Four Epigenetic Variants Along Individual DNA Strands”

Yaniv Erlich, Whitehead Institute for Biomedical Research
“Genome-Wide Analysis of Expression Short Tandem Repeats”

Carlos Bustamante, Stanford University
“Any Way You Want It: Applications of Whole Genome Capture to Ancient DNA, Metagenomics, and Orthogonal Validation”

Daniel MacArthur, Massachusetts General Hospital
“Functional Annotation at Scale:  Analysis of Genetic Variation From Over 50,000 Human Exomes”

Genohub will be in attendance and tweeting @Genohub. Send us a message and let’s meetup to talk NGS !