The “$1K”, 30X Whole Human Genome is now available for $1,400

HiSeq X Ten Sequencing Services now Available on Genohub

You can now order whole human genome sequencing (~30x coverage) on for $1,400 / sample ($1,550 with library prep). The Kinghorn Centre for Clinical Genomics is accepting orders for their HiSeq X Ten service through  In fact, you can order this service today:

Designed for population scale human genome sequencing, the HiSeq X Ten when operating individually can output between 1.6-1.8 Tb on a dual flow cell in less than 3 days (600 Gb / day). When running 10 in parallel, tens of thousands of genomes can be sequenced in a single year. While currently Illumina has limited the HiSeq X Ten to human samples, we expect this will change in 2015. 

A single lane of HiSeq X Ten, gives you 750M paired end 2x 150 reads, for a total output of 112.5 Gb / lane. Kinghorn guarantees 100 Gb raw data per lane, with >75% of bases above Q30 at 2x150bp. With a haploid human genome size of 3.2 Gb, that’s equivalent to 30-35x  per lane of sequencing.  The $10 million price tag for the HiSeq X Ten means that not all institutes have access to such sequencing power. Genohub solves this problem by making it easy for researchers interested in next generation sequencing services to access all the latest sequencing technology. We also:

  1. Ensure your project with the provider goes smoothly
  2. Take care of billing and invoicing, making domestic & international ordering a breeze
  3. Have an easy to use project management interface to keep communication and information in one place
  4. Offer NGS project design and consultation
  5. Have competitive pricing and turnaround times

Start your population study on today !




UTHSCSA Lists Next Generation Sequencing Services On Genohub

Genohub would like to welcome the Genome Sequencing Facility (GSF) at Greehey Children’s Cancer Research Institute in the University of Texas Health Science Center at San Antonio to the Genohub family. The sequencing services listed by UTHSCSA has added more available options for researchers on the Genohub next generation sequencing market.

UTHSCSA listed the following next generation sequencing instruments and Illumina library preparation options:

  • Instruments:
    • Illumina MiSeq paired end sequencing options
    • Illumina HiSeq single read and paired end sequencing options
  • Library prep:
    • Illumina ChIP
    • Illumina Directional RNA (polyA-selected)
    • Illumina Directional RNA (rRNA-depleted)
    • Illumina DNA
    • Illumina Exome
    • Illumina RNA (polyA-selected)
    • Illumina RNA (rRNA-depleted)
    • Illumina Small RNA (microRNA)

The GSF has a stated mission to deploy NGS systems focusing on cancer genomics to benefit Greehey CCRI investigators and the wider research community. The NGS facility performs all protocols necessary for preparing a sample to be sequenced on the Illumina HiSeq 2000 system. The GSF is also a research group with experience in customizing experiments and developing new applications. They provide:

  • Complete project consultation for optimal experimental design and setup
  • Complete quality control analysis during library preparation and data generation
  • Secure website to download the sequencing data with quality information
  • Full project report
  • Bioinformatics analysis option available
  • NCBI GenBank submission option available

We are excited to include UTHSCSA high throughput sequencing services on the Genohub next generation sequencing market.

SUNY Buffalo Lists Services On the Genohub Next Generation Sequencing Market

Genohub would like to welcome The University at Buffalo Next-Generation Sequencing and Expression Analysis Core Facility (UB Next-Gen Core), which includes the Western New York Stem Cell Sequencing and Epigenomics Core (WNYSTEM). The sequencing services listed by SUNY will add more available options to the Genohub next generation sequencing market.

SUNY listed the following next generation sequencing instruments and library prep options:

  • Instruments:
    • Illumina HiSeq paired end sequencing and single read sequencing options
  • Library prep:
    • Illumina DNA
    • Illumina ChIP
    • Illumina Small RNA (microRNA)
    • Illumina RNA (polyA-selected)

The SUNY Core Facility is located on the Buffalo Niagara Medical Campus at the New York State Center of Excellence in Bioinformatics and Life Sciences. They are the first next-generation sequencing service provider in Western New York. We look forward to matching SUNY Buffalo with the most compatible high throughput sequencing projects for their lab.

For Academic Genome Centers: How Genohub Fits into the NIH Circular A21 Picture

Occasionally, we speak with directors at academic genome centers that express their interest in Genohub, yet are unsure whether listing their high throughput sequencing services would in some way be unauthorized under NIH Circular A21. This circular “Establishes principles for determining costs applicable to grants, contracts, and other agreements with educational institutions”. Of course this directive does not affect all academic genome centers, but there are a substantial number which do receive grant funding from the NIH.

The general concern regarding how Genohub fits into the Circular A21 picture is understandable. The concern can likely be attributed to subsection J.46 which states:

Costs of selling and marketing any products or services of the institution are unallowable (unless allowed under subsection J.1 as allowable public relations costs or under subsection J.38 as allowable proposal costs).

Clearly, it would not be permissible for academic genome centers under Circular A21 to pay a third party to market their sequencing services. For this reason (among others), high throughput sequencing services are completely free to list on the Genohub Next Generation Sequencing Market. There are also currently no provisions whereby sequencing providers are able to pay Genohub for marketing services. Of course Genohub engages in marketing practices which happen to be aligned with the external facing goals of  many academic genome centers, namely attracting and offering the best value to researchers with projects involving next generation sequencing. Service providers do benefit from Genohub marketing, albeit at no cost.

Selling, on the other hand, can be viewed as permissible on Genohub under the subsection J.38 exception as an allowable proposal cost. Circular A21, J.38 states:

Proposal costs are the costs of preparing bids or proposals on potential federally and non federally funded sponsored agreements or projects, including the development of data necessary to support the institution’s bids or proposals. Proposal costs of the current accounting period of both successful and unsuccessful bids and proposals normally should be treated as F&A costs and allocated currently to all activities of the institution, and no proposal costs of past accounting periods will be allocable to the current period. However, the institution’s established practices may be to treat proposal costs by some other recognized method. Regardless of the method used, the results obtained may be accepted only if found to be reasonable and equitable.

Under the J.38 exception, Genohub offers the following service at a nominal fee per transaction through Genohub:

“Preparing bids or proposals”: One of the biggest reasons providers list services on Genohub is because they save valuable time and cost preparing bids or proposals. Services and pricing are listed one time only by the provider. Any time a researcher visits and shops for services via the Genohub shopping interface, Genohub instantly and automatically prepares and delivers bids from every NGS provider that meets the minimum search criteria. Of course Genohub only charges a small fee to the provider whose bid is chosen by the researcher.

The time and money saved on proposal costs by using Genohub has freed up resources for academic genome centers to allow them to refocus on their core objectives within their institution, yet fill those needed external sequencing orders to keep the engines running. Time and cost is further reduced as we offer researchers free consultation from our science team that might otherwise be required of the provider. We hope to continue to increase the value we provide to academic genome centers and researchers alike by creating a beautiful, simple, and cost effective next generation sequencing market.

If you have any additional questions on Circular A21 as it relates to Genohub, or have any feedback on how we can improve the services we offer to you, our valued customers, we encourage you to contact us at


University of Rochester Genomics Research Center Adds High Throughput Sequencing Services to Genohub

We want to welcome the University of Rochester Genomics Research Center to the Genohub family. The high throughput sequencing services listed by the University of Rochester will add more available options to the Genohub next generation sequencing market.

The University of Rochester added the following instruments and library prep options:

  • Instruments: Illumina HiSeq
  • Library prep: a host of Illumina options
    • Directional RNA (rRNA-depleted)
    • Directional RNA (polyA-selected)
    • Small RNA (microRNA)
    • ChIP
    • Mate Pair (1-6 kb)
    • DNA
    • Bisulfite
    • RNA (polyA-selected)

We look forward to matching the University of Rochester with the most compatible high throughput sequencing orders for their lab.